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0
2/10
Stanford Medicine researchers developed a novel intranasal vaccine that protects against diverse respiratory viruses, bacteria, and allergens by mimicking T cell signals that sustain innate immune responses for months, rather than using traditional antigen-specific approaches. The vaccine combines toll-like receptor stimuli with a harmless antigen to create a feedback loop between innate and adaptive immunity, providing broad cross-protection in mice against SARS-CoV-2, coronaviruses, hospital-acquired pathogens, and dust mites.
vaccine-development
innate-immunity
adaptive-immunity
respiratory-infections
intranasal-vaccine
universal-vaccine
toll-like-receptors
sars-cov-2
coronavirus
bacterial-infections
allergen-protection
immunology
t-cell-signaling
cytokines
dendritic-cells
Stanford Medicine
Bali Pulendran
Haibo Zhang
Science
GLA-3M-052-LS+OVA
SARS-CoV-2
Staphylococcus aureus
Acinetobacter baumannii
Edward Jenner